ログイン 会員登録
icon_bulk_order一括注文 Acrobiosystems for English
Promotion
Recombinantタンパク質s ClearClear history
Recombinantタンパク質s CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
phone
Your Position: ホーム > Cadherin-6

Cadherin-6

概要

Name:Cadherin-6
Target Synonym:Kidney cadherin,K-cadherin,Cadherin 6, Type 2, K-Cadherin (Fetal Kidney),K-Cadherin,Cadherin-6,Kidney Cadherin,CAD6,KCAD
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 3 Clinical

Antibody Licensing

Project Name Project Stage Molecule Type Host Species Therapeutic Area Indications
CDH6 mAb - 01 PCC Solid Tumor Ovarian cancer,Renal cell carcinoma

製品リスト製品比較と製品注文

製品> フィルター結果
製品仕様別：
製品カテゴリー別：
種類別：
タグ別：
コンジュゲート：
製造番号 種類 製品説明 構造 純度 特徴
CHEK-ATP127 Human HEK293/Human Cadherin-6 Stable Cell Line
CA6-H82E3 Human Biotinylated Human Cadherin-6 / KCAD / CDH6 Protein, His,Avitag™ (MALS verified)
CA6-H82E3-structure
CA6-H82E3-sds
CA6-M52H8 Mouse Mouse Cadherin-6 / KCAD / CDH6 Protein, His Tag
CA6-M52H8-structure
CA6-M52H8-sds
CA6-C52H3 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque Cadherin-6 / KCAD / CDH6 Protein, His Tag
CA6-C52H3-structure
CA6-C52H3-sds
CA6-H5258 Human Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified)
CA6-H5258-structure
CA6-H5258-sds
CA6-H5229 Human Human Cadherin-6 / KCAD / CDH6 Protein, His Tag
CA6-H5229-structure
CA6-H5229-sds
ACRO Quality

生物活性データの一部

CHEK-ATP127-Cell-based assay
Cadherin-6 FACS

Expression analysis of human Cadherin-6 on HEK293/Human Cadherin-6 Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Cadherin-6 Stable Cell Line or negative control cell using anti-human Cadherin-6 antibody followed by staining with PE anti-human IgG Fc antibody.

Protocol
CA6-M52H8-ELISA
Cadherin-6 ELISA

Immobilized Mouse Cadherin-6, His Tag (Cat. No. CA6-M52H8) at 1 μg/mL (100 μL/well) can bind Human Cadherin-6 Antibody, Mouse IgG1 with a linear range of 0.1-1 ng/mL (QC tested).

Protocol
CA6-H82E3-MALS-HPLC
Cadherin-6 MALS images

The purity of Biotinylated Human Cadherin-6 Protein, His,Avitag (Cat. No. CA6-H82E3) is more than 90% and the molecular weight of this protein is around 75-100 kDa verified by SEC-MALS.

カスタマーレビュー

Synonym Name

CDH6,CAD6,KCAD,K-cadherin,Cadherin-6

Background

Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a  a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.

Clinical and Translational Updates

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Raludotatug deruxtecan DS-6000a; DS6000a; DS-6000; R-DXd Phase 3 Clinical Daiichi Sankyo Co Ltd Ovarian Neoplasms; Solid tumours; Carcinoma, Renal Cell; Peritoneal Neoplasms; Fallopian Tube Neoplasms Details
AMT-707 AMT-707; CUSP-06 Phase 1 Clinical Multitude Therapeutics Inc Solid tumours; Ovarian Neoplasms; Carcinoma, Renal Cell; Cholangiocarcinoma Details
Raludotatug deruxtecan DS-6000a; DS6000a; DS-6000; R-DXd Phase 3 Clinical Daiichi Sankyo Co Ltd Ovarian Neoplasms; Solid tumours; Carcinoma, Renal Cell; Peritoneal Neoplasms; Fallopian Tube Neoplasms Details
AMT-707 AMT-707; CUSP-06 Phase 1 Clinical Multitude Therapeutics Inc Solid tumours; Ovarian Neoplasms; Carcinoma, Renal Cell; Cholangiocarcinoma Details

This web search service is supported by Google Inc.

totopphone
Call us
お問い合わせ
グローバル：+1 800-810-0816(Toll Free)
日本：+(0)81-50-547-99099
Email
メールアドレス
order.jp@acrobiosystems.com
Fax
ファックス
+1 888-377-6111
Address
株式会社アクロバイオシステムズ
〒157-0066
東京都世田谷区成城1丁目26番9-101号

アクロバイオシステムズの公式アカウント

linkedin twitter facebook youtube

お問い合わせ（半角英文字で入力してください）

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap