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IL-35

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製造番号 種類 製品説明 構造 純度 特徴
IL5-H5259 Human Human IL-35 Protein, Fc Tag
IL5-H5259-sds
ACRO Quality

生物活性データの一部

IL5-H5259-ELISA
 IL-35 ELISA

Immobilized Human IL-35 R, His Tag (Cat. No. ILR-H52H8) at 5 μg/mL (100 μL/well) can bind Human IL-35, Fc Tag (Cat. No. IL5-H5259) with a linear range of 0.002-0.625 μg/mL (QC tested).

Synonym Name

EBI3,IL35,IL-35EBI3,IL35p35,Interleukin-35,IL-35

Background

Interleukin 35 (IL-35) is a recently discovered anti-inflammatory cytokine from the IL-12 family. Member of IL-12 family - IL-35 is produced by wide range of regulatory lymphocytes and plays a role in immune suppression. IL-35 can block the development of Th1 and Th17 cells by limiting early T cell proliferation. The heterodimeric cytokine of IL-35 involves two subunits of p35 and Ebi3 which are also seen in IL-12 and IL-27.  IL-35 is recognized as a defi nite immunosuppressor with a huge potent of suppression.

Clinical and Translational Updates

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