Number of Launched Drugs:0 Number of Drugs in Clinical Trials:7 Lastest Research Phase:Phase 3 Clinical
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Synonym Name
NMDAR2B
Background
NMDA receptors (NMDARs) are members of the glutamate-gated ion-channel family that mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation.
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