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CXCR3

概要

Name:C-X-C motif chemokine receptor 3
Target Synonym:CKR-L2,G protein-coupled receptor 9,IP-10 receptor,CXCR-3,CXC-R3,CXCR3,C-X-C Motif Chemokine Receptor 3,Interferon-Inducible Protein 10 Receptor,GPR9,C-X-C Chemokine Receptor Type 3,Chemokine Receptor 3,CD183 Antigen,CMKAR3,Chemokine (C-X-C Motif) Receptor 3,Mig Receptor,IP10-R,CD182,CD183,Mig-R,MigR,Receptors, CXCR3
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 1 Clinical

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製造番号 種類 製品説明 構造 純度 特徴
CX3-M52P7 Mouse Mouse CXCR3 Full Length Protein (VLP)
CX3-H52D5 Human Human CXCR3 Protein, Flag,His Tag (Detergent)
CX3-H52D5-structure
CX3-H52P4 Human Human CXCR3 Full Length Protein (VLP)
ACRO Quality

生物活性データの一部

CX3-H52P4-SPR
 CXCR3 SPR

Anti-CXCR3 antibody immobilized on CM5 Chip can bind Human CXCR3 Full Length Protein-VLP (Cat. No. CX3-H52P4) with an affinity constant of 60.9 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

CX3-H52D5-ELISA
 CXCR3 ELISA

Immobilized Human CXCR3 Protein, Flag,His Tag (Cat. No. CX3-H52D5) at 1 μg/mL (100 μL/well) can bind Anti-CXCR3 Antibody, Human IgG1 with a linear range of 0.03-1 ng/mL (QC tested).

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
OCU-110 OCU-110; OCU-10-C-110 Phase 1 Clinical Ocugenix Corp Macular Degeneration Details
ACT-777991 ACT-777991 Phase 1 Clinical Idorsia Pharmaceuticals Ltd Inflammation Details

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