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Your Position: ホーム > Galectin-3

Galectin-3

概要

Name:Galectin-3
Target Synonym:Galactoside-binding protein,GALBP,Epididymis Secretory Sperm Binding Protein,MAC2,Laminin-binding protein,CBP 35,Gal-3,IgE-binding protein,Carbohydrate-binding protein 35,L-31,Lectin L-29,LGALS3,Advanced Glycation End-Product Receptor 3,Lectin, Galactoside-Binding, Soluble, 3,Galactose-Specific Lectin 3,35 KDa Lectin,Mac-2 Antigen,Galectin-3,LGALS2,CBP35,GALIG,GAL3,L31,Galectin 3,MAC-2
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:6
Lastest Research Phase:Approved

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製造番号 種類 製品説明 構造 純度 特徴
GA3-H5247 Human Human Galectin-3 Protein, His Tag
GA3-H5247-structure
GA3-H5247-sds
GA3-H5129 Human Human Galectin-3 Protein, His Tag (MALS verified)
GA3-H5129-structure
GA3-H5129-sds
ACRO Quality

生物活性データの一部

GA3-H5129-MALS-HPLC
Galectin-3 MALS images

The purity of Human Galectin-3, His Tag (Cat. No. GA3-H5129) is more than 90% and the molecular weight of this protein is around 23-35 kDa verified by SEC-MALS.

Synonym Name

Galectin-3,LGALS3,MAC2,Gal-3,35 kDa lectin,CBP 35,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen

Background

Galectin-3 (Gal-3) is also known as LGALS3, 35 kDa lectin, Carbohydrate-binding protein 35 (CBP 35), Galactose-specific lectin 3, Galactoside-binding protein (GALBP), IgE-binding protein, Laminin-binding protein, Mac-2 antigen, Lectin L-29. Galectin-3 is a member of the lectin family. LGALS3 / Galectin-3 is expressed in the nucleus, cytoplasm, mitochondrion, cell surface, and extracellular space. LGALS3 / Galectin-3 has been shown to be involved in the following biological processes: cell adhesion, cell activation and chemoattraction, cell growth and differentiation, cell cycle, and apoptosis.

Clinical and Translational Updates

公開薬物情報

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Ocriplasmin A-01016; THR-409 Approved Thrombogenics Jetrea, Jejetrea United States Vitreomacular Adhesion Thrombogenics Inc 2012-10-17 Vitreous Detachment; Arterial Occlusive Diseases; Disease Progression; Stroke; Retinal Diseases; Diabetic macular oedema; Uveitis; Vitreomacular Adhesion; Venous Thrombosis; Eye Diseases; Macular Degeneration; Diabetic Retinopathy; Retinal Vein Occlusion Details
Ocriplasmin A-01016; THR-409 Approved Thrombogenics Jetrea, Jejetrea United States Vitreomacular Adhesion Thrombogenics Inc 2012-10-17 Vitreous Detachment; Arterial Occlusive Diseases; Disease Progression; Stroke; Retinal Diseases; Diabetic macular oedema; Uveitis; Vitreomacular Adhesion; Venous Thrombosis; Eye Diseases; Macular Degeneration; Diabetic Retinopathy; Retinal Vein Occlusion Details

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Belapectin GR-MD-02 Phase 3 Clinical Galectin Therapeutics Inc Metabolic Dysfunction-Associated Steatotic Liver Disease; Squamous Cell Carcinoma of Head and Neck; Fibrosis; Hypertension, Portal; Psoriasis; Hepatic Insufficiency; Esophageal and Gastric Varices; Melanoma; Carcinoma, Non-Small-Cell Lung Details
ProLectin-M Phase 3 Clinical BioXyTran Inc Cytokine Release Syndrome; Coronavirus Disease 2019 (COVID-19); Influenza, Human Details
Olitigaltin GB-0139; TD-139 Phase 2 Clinical The University Of Edinburgh, Lund University Foundation Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19) Details
Galactomannan C GM-CT-01 Phase 2 Clinical Galectin Therapeutics Inc Head and Neck Neoplasms; Coronavirus Disease 2019 (COVID-19); Small Cell Lung Carcinoma; Breast Neoplasms; Prostatic Neoplasms; Coronaviridae Infections; Colorectal Neoplasms; Bile Duct Neoplasms; Lung Neoplasms; Gallbladder Neoplasms; Melanoma Details
Selvigaltin GB-1211; GB1211 Phase 2 Clinical Galecto Inc Squamous Cell Carcinoma of Head and Neck; Metabolic Dysfunction-Associated Steatotic Liver Disease; Hepatic Insufficiency; Melanoma; Carcinoma, Non-Small-Cell Lung Details
Gal-400 Gal-400 Phase 1 Clinical Galecto Inc Metabolic Dysfunction-Associated Steatotic Liver Disease; Liver Cirrhosis Details
Belapectin GR-MD-02 Phase 3 Clinical Galectin Therapeutics Inc Metabolic Dysfunction-Associated Steatotic Liver Disease; Squamous Cell Carcinoma of Head and Neck; Fibrosis; Hypertension, Portal; Psoriasis; Hepatic Insufficiency; Esophageal and Gastric Varices; Melanoma; Carcinoma, Non-Small-Cell Lung Details
ProLectin-M Phase 3 Clinical BioXyTran Inc Cytokine Release Syndrome; Coronavirus Disease 2019 (COVID-19); Influenza, Human Details
Olitigaltin GB-0139; TD-139 Phase 2 Clinical The University Of Edinburgh, Lund University Foundation Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19) Details
Galactomannan C GM-CT-01 Phase 2 Clinical Galectin Therapeutics Inc Head and Neck Neoplasms; Coronavirus Disease 2019 (COVID-19); Small Cell Lung Carcinoma; Breast Neoplasms; Prostatic Neoplasms; Coronaviridae Infections; Colorectal Neoplasms; Bile Duct Neoplasms; Lung Neoplasms; Gallbladder Neoplasms; Melanoma Details
Selvigaltin GB-1211; GB1211 Phase 2 Clinical Galecto Inc Squamous Cell Carcinoma of Head and Neck; Metabolic Dysfunction-Associated Steatotic Liver Disease; Hepatic Insufficiency; Melanoma; Carcinoma, Non-Small-Cell Lung Details
Gal-400 Gal-400 Phase 1 Clinical Galecto Inc Metabolic Dysfunction-Associated Steatotic Liver Disease; Liver Cirrhosis Details

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