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IGFBP-1

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製造番号 種類 製品説明 構造 純度 特徴
IG1-H52H3 Human Human IGFBP-1 Protein, His Tag (MALS verified)
IG1-H52H3-structure
IG1-H52H3-sds
ACRO Quality

生物活性データの一部

IG1-H52H3-MALS-HPLC
IGFBP-1 MALS images

The purity of Human IGFBP-1 Protein, His Tag (Cat. No. IG1-H52H3) is more than 90% and the molecular weight of this protein is around 22-32 kDa verified by SEC-MALS.

IG1-H52H3-ELISA
 IGFBP-1 ELISA

Immobilized Human IGF-I, Fc Tag at 5 μg/mL (100 μL/well) can bind Human IGFBP-1 Protein, His Tag (Cat. No. IG1-H52H3) with a linear range of 0.01-0.156 μg/mL (QC tested).

Synonym Name

IGFBP1,PP12,IBP1

Background

Insulin-like growth factor-binding protein 1 (IGFBP1) is also known as placental protein 12 (PP12), which contains oneIGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP1 can bindd both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of IGFBP1 can prolongd the half-life of the IGFs and alterd their interaction with cell surface receptors. Furthermore, IGFBP1 can promote cell migration. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Clinical and Translational Updates

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