ログイン 会員登録
icon_bulk_order一括注文 Acrobiosystems for English
Promotion
Recombinantタンパク質s ClearClear history
Recombinantタンパク質s CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
phone
Your Position: ホーム > IL-1RL1

IL-1RL1

概要

Name:Interleukin-1 receptor-like 1
Target Synonym:ST2,IL1RL1,Protein ST2,DER4,T1,Interleukin 1 Receptor Like 1,Homolog Of Mouse Growth Stimulation-Expressed,Interleukin 1 Receptor-Related Protein,Growth Stimulation-Expressed,FIT-1,IL33R,ST2L,ST2V,Interleukin-1 Receptor-Like 1 Protein,EC:3.2.2.6,Interleukin-1 Receptor-Like 1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:5
Lastest Research Phase:NDA/BLA

製品リスト製品比較と製品注文

製品> フィルター結果
製品仕様別：
製品カテゴリー別：
種類別：
タグ別：
コンジュゲート：
製造番号 種類 製品説明 構造 純度 特徴
IL1-H82F8 Human Biotinylated Human IL-1RL1 / ST2 Protein, Fc,Avitag™ (MALS verified)
IL1-H82F8-structure
IL1-H82F8-sds
IL1-M5259 Mouse Mouse IL-1RL1 / ST2 Protein, Fc Tag
IL1-M5259-structure
IL1-M5259-sds
IL1-H82E9 Human Biotinylated Human IL-1RL1 / ST2 Protein, His,Avitag™ (MALS verified)
IL1-H82E9-structure
IL1-H82E9-sds
IL1-H5250 Human Human IL-1RL1 / ST2 Protein, Fc Tag
IL1-H5250-structure
IL1-H5250-sds
IL1-H5229 Human Human IL-1RL1 / ST2 Protein, His Tag (MALS verified)
IL1-H5229-structure
IL1-H5229-sds
ACRO Quality

生物活性データの一部

IL1-H5250-BLI
IL-1RL1 BLI

Loaded Human IL-1RL1, Fc Tag (Cat. No. IL1-H5250) on Protein A Biosensor, can bind with Biotinylated Human IL-33, His,Avitag (Cat. No. IL3-H82H5) an affinity constant of 1.81 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
IL1-H82E9-ELISA
IL-1RL1 ELISA

Immobilized Human IL-33 Protein, His Tag (Cat. No. IL3-H52H7) at 5 μg/mL (100 μL/well) can bind Biotinylated Human IL-1RL1, His,Avitag (Cat. No. IL1-H82E9) with a linear range of 0.3-10 ng/mL (QC tested).

Protocol

Synonym Name

IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1

Background

Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.

Clinical and Translational Updates

相関分子

IL-33

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Astegolimab AMG-282; RG-6149; RO-7187807 Phase 3 Clinical Amgen Inc, F. Hoffmann-La Roche Ltd Coronavirus Disease 2019 (COVID-19); Pulmonary Disease, Chronic Obstructive; Dermatitis, Atopic Details
Recombinant humanized anti-ST2 monoclonal antibody 9-MW1911; 9MW-1911; 9-MW-1911; 9MW1911 Phase 2 Clinical Mabwell (Shanghai) Bioscience Co Ltd Asthma; Pulmonary Disease, Chronic Obstructive; Dermatitis, Atopic Details
Melrilimab GSK-3772847; CNTO-7160 Phase 2 Clinical Johnson & Johnson Innovative Medicine Asthma Details
TQC-2938 TQC2938; TQC-2938 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Asthma Details
Astegolimab AMG-282; RG-6149; RO-7187807 Phase 3 Clinical Amgen Inc, F. Hoffmann-La Roche Ltd Coronavirus Disease 2019 (COVID-19); Pulmonary Disease, Chronic Obstructive; Dermatitis, Atopic Details
Recombinant humanized anti-ST2 monoclonal antibody 9-MW1911; 9MW-1911; 9-MW-1911; 9MW1911 Phase 2 Clinical Mabwell (Shanghai) Bioscience Co Ltd Asthma; Pulmonary Disease, Chronic Obstructive; Dermatitis, Atopic Details
Melrilimab GSK-3772847; CNTO-7160 Phase 2 Clinical Johnson & Johnson Innovative Medicine Asthma Details
TQC-2938 TQC2938; TQC-2938 Phase 1 Clinical Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group Asthma Details

This web search service is supported by Google Inc.

totopphone
Call us
お問い合わせ
グローバル：+1 800-810-0816(Toll Free)
日本：+(0)81-50-547-99099
Email
メールアドレス
order.jp@acrobiosystems.com
Fax
ファックス
+1 888-377-6111
Address
株式会社アクロバイオシステムズ
〒157-0066
東京都世田谷区成城1丁目26番9-101号

アクロバイオシステムズの公式アカウント

linkedin twitter facebook youtube

お問い合わせ（半角英文字で入力してください）

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap