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Expression analysis of human Transferrin on HEK293/Human Transferrin Stable Cell Line by FACS.
Cell surface staining was performed on HEK293/Human Transferrin Stable Cell Line or negative control cell using PE-labeled anti-human Transferrin antibody.
Biotinylated Human Transferrin Protein, His,Avitag (Cat. No. TRN-H82E3) captured on Biotin CAP-Series S Sensor Chip can bind Human Transferrin R, His Tag (Cat. No. CD1-H5243) with an affinity constant of 0.527 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Immobilized Biotinylated Human Transferrin R Protein, Fc,Avitag (Cat. No. TFR-H82F3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Biotinylated Human Transferrin R Protein, Fc,Avitag (Cat. No. TRN-H52H3) with a linear range of 5-78 ng/mL (QC tested).
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Tisotumab vedotin | TF-011-MMAE | Approved | Genmab A/S | HuMax-TF, TIVDAK | United States | Uterine Cervical Neoplasms | Seagen Inc | 2021-09-20 | Ovarian Neoplasms; Solid tumours; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Anpocogin | AB-201 | Phase 3 Clinical | Dendreon Uk Ltd | Coronavirus Disease 2019 (COVID-19) | Details |
| XNW-28012 | XNW-28012; XNW28012 | Phase 2 Clinical | Shanghai Cigna Biotech Pharmaceutical Co Ltd | Solid tumours | Details |
| MRG-004A | MRG004A | Phase 2 Clinical | Shanghai Miracogen Inc | Solid tumours | Details |
| XB-002 | XB-002; ICON-2 | Phase 1 Clinical | Iconic Therapeutics Inc | Solid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Urogenital Neoplasms; Esophageal Squamous Cell Carcinoma; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms | Details |
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