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Vasorin

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製造番号 種類 製品説明 構造 純度 特徴
VAN-H52H3 Human Human Vasorin / VASN Protein, His Tag
VAN-H52H3-structure
VAN-H52H3-sds
ACRO Quality

Synonym Name

VASN,SLITL2,Vasorin

Background

Vasorin (VASN),a single-pass type I membrane protein, is also known as protein slit-like 2 and SLITL2, which contains one EGF-like domain, ten LRR (leucine-rich) repeats, one LRRCT domain and one LRRNT domain. VASN is expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. VASN can interact selectively and non-covalently with TGF-beta, transform growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. In general, VASN may act as an inhibitor of TGF-beta signaling.

Clinical and Translational Updates

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