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CD300a

概要

Name:CMRF35-like molecule 8
Target Synonym:CLM-8,CD300 antigen-like family member A,CMRF-35-H9 (CMRF35-H9),CMRF35-H,IRC1/IRC2,Immunoglobulin superfamily member 12 (IgSF12),Inhibitory receptor protein 60 (IRp60),NK inhibitory receptor
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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製造番号 種類 製品説明 構造 純度 特徴
CDA-H52H5 Human Human CD300a / LMIR1 Protein, His Tag (MALS verified)
CDA-H52H5-structure
CDA-H52H5-sds
ACRO Quality

生物活性データの一部

The purity of Human CD300a Protein, His Tag (Cat. No. CDA-H52H5) is more than 85% and the molecular weight of this protein is around 16-24 kDa verified by SEC-MALS.

Synonym Name

CD300A,CLM-8,CMRF-35-H9,CMRF35-H9,CMRF35-H,IRC1/IRC2,IgSF12,IRp60,CMRF35H,IGSF12,LMIR1

Background

CD300 antigen-like family member A (CD300A) is also known as CMRF35-like molecule 8 (CLM-8), CMRF-35-H9, CMRF35-H, Immunoglobulin superfamily member 12 (IGSF12), NK inhibitory receptor, LMIR1, which belongs to the CD300 family. CD300A contains one Ig-like V-type (immunoglobulin-like) domain. CD300A is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is a inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

Clinical and Translational Updates

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