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LILRA2

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製造番号 種類 製品説明 構造 純度 特徴
LI2-H52H3 Human Human LILRA2 / CD85h / ILT1 Protein, His Tag
LI2-H52H3-structure
LI2-H52H3-sds
LI2-H82E9 Human Biotinylated Human LILRA2 / CD85h / ILT1 Protein, His,Avitag™
LI2-H82E9-structure
LI2-H82E9-sds
ACRO Quality

Synonym Name

ILT1, LIR7, CD85H, LIR-7, LILRA2, ILT1CD85H, CD85h, ILT1, ILT-1, ILT1CD85H, CD85h antigen, CD85 antigen-like family member H

Background

LILRA2 (Leukocyte immunoglobulin like receptor A2), also known as CD85H and LIR7 (Leukocyte immunoglobulin-like receptor 7). It belongs to the subfamily A class of LIR receptors (LILRAs), which are single-pass type I transmembrane proteins with 2-4 extracellular Ig-like domains, a transmembrane domain (TM), and a short cytoplasmic tail.  LILRA2 contains 4 Ig-like C2 type domains in the extracellular region. LILRA2 does not bind class I MHC antigens. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response.

Clinical and Translational Updates

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