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CD24

概要

Name:Signal transducer CD24
Target Synonym:Small cell lung carcinoma cluster 4 antigen,CD24A,CD24 Antigen (Small Cell Lung Carcinoma Cluster 4 Antigen),CD24 Molecule,CD24 Antigen
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:5
Lastest Research Phase:Phase 2 Clinical

製品リスト製品比較と製品注文

ACRO Quality

生物活性データの一部

CD4-H52H5-ELISA
 CD24 ELISA

Immobilized Human CD24 Protein, His Tag (Cat. No. CD4-H52H5) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 5-78 ng/mL (QC tested).

CD4-H5246-ELISA
 CD24 ELISA

Immobilized Human CD24, His Tag-Ferritin (Cat. No. CD4-H5246) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 10-625 ng/mL (QC tested).

Synonym Name

CD24,CD24A

Background

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Clinical and Translational Updates

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
IBD-0333 IBD-0333; IBD0333 Phase 2 Clinical SunHo (China) BioPharmaceutical Co Ltd Solid tumours; Neoplasms; Lymphoma, Non-Hodgkin Details
ATG-031 ATG-031; ATN-031 Phase 1 Clinical Antengene Corporation Co Ltd Lymphoma, B-Cell; Solid tumours; Hematologic Neoplasms Details
NXA-01 NXA01; NXA-01 Phase 1 Clinical Beijing Xingkangyuan Biotechnology Co Ltd Solid tumours Details
KH-801 KH-801; KH801 Phase 1 Clinical Chengdu Kanghong Pharmaceutical Group Co Ltd Solid tumours; Neoplasms Details
ONC-841 ONC-841 Phase 1 Clinical Oncoimmune-Guangzhou Solid tumours; Neoplasms Details
IBD-0333 IBD-0333; IBD0333 Phase 2 Clinical SunHo (China) BioPharmaceutical Co Ltd Solid tumours; Neoplasms; Lymphoma, Non-Hodgkin Details
ATG-031 ATG-031; ATN-031 Phase 1 Clinical Antengene Corporation Co Ltd Lymphoma, B-Cell; Solid tumours; Hematologic Neoplasms Details
NXA-01 NXA01; NXA-01 Phase 1 Clinical Beijing Xingkangyuan Biotechnology Co Ltd Solid tumours Details
KH-801 KH-801; KH801 Phase 1 Clinical Chengdu Kanghong Pharmaceutical Group Co Ltd Solid tumours; Neoplasms Details
ONC-841 ONC-841 Phase 1 Clinical Oncoimmune-Guangzhou Solid tumours; Neoplasms Details

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