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PD-1

概要

Name:Programmed cell death protein 1
Target Synonym:Programmed cell death protein 1,CD279,hPD-1,PDCD1,Programmed Cell Death 1,Systemic Lupus Erythematosus Susceptibility 2,Protein PD-1,PD1,Programmed Cell Death 1 Protein,CD279 Antigen,HPD-L,HSLE1,SLEB2,PD-1,Programmed Cell Death 1 Receptor
Number of Launched Drugs:20
Number of Drugs in Clinical Trials:167
Lastest Research Phase:Phase 3 Clinical

Antibody Licensing

Project Name Project Stage Molecule Type Host Species Therapeutic Area Indications
PD-1 VHH mAb - 01 PCC Solid Tumor Solid tumor

ライセンス

Project Name Modality Therapeutic Area Indications Stage Right Available
SIRPα×PD-1 bsAb Bispecific antibody Oncology/Cancer Advanced solid tumor Preclinical Global
PD-1×TIGIT BsAb for Advanced solid tumor Bispecific antibody Oncology/Cancer Cancer Preclinical Global

製品リスト製品比較と製品注文

製造番号 種類 製品説明 構造 純度 特徴
PD1-M52H3 Mouse Mouse PD-1 / PDCD1 Protein, His Tag (MALS verified)
PD1-M52H3-structure
PD1-M52H3-sds
CHEK-ATP143 Human HEK293/Human PD-1 Stable Cell Line
PD1-M82E3 Mouse Biotinylated Mouse PD-1 / PDCD1 Protein, His,Avitag™ (MALS verified)
PD1-M82E3-structure
PD1-M82E3-sds
PD1-M5257 Mouse Mouse PD-1 / PDCD1 Protein, Mouse IgG2a Fc Tag (MALS verified)
PD1-M5257-structure
PD1-M5257-sds
PD1-C82F7 Cynomolgus Biotinylated Cynomolgus PD-1 / PDCD1 Protein, Fc,Avitag™ (MALS verified)
PD1-C82F7-structure
PD1-C82F7-sds
HGS-S238 Mouse Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3)
PD1-H5286 Human Human PD-1 / PDCD1 Protein, Twin-Strep Tag (MALS verified)
PD1-H5286-structure
PD1-H5286-sds
EP-154 Human PD-1 : PD-L2 [Biotinylated] Inhibitor Screening ELISA Kit
PD1-C52H5 Cynomolgus Cynomolgus PD-1 / PDCD1 Protein, His Tag (MALS verified)
PD1-C52H5-structure
PD1-C52H5-sds
RAB-P002 Human Human Anti-PD-1 Antibody IgG Titer Serologic ELISA Assay Kit
PD1-C52E5 Canine Biotinylated Canine PD-1 / PDCD1 Protein, His,Avitag™ (MALS verified)
PD1-C52E5-structure
PD1-C52E5-sds
EP-120 Human PD-1 [Biotinylated] : PD-L2 Inhibitor Screening ELISA Kit
EP-130 Human PD-1 : PD-L1 [Biotinylated] Inhibitor Screening ELISA Kit
PD1-H5256 Human Human PD-1 / PDCD1 Protein, Fc,His Tag
PD1-H5256-structure
PD1-H5256-sds
PD1-H52H2 Human Human PD-1 Protein, His Tag (Nanoparticle)
PD1-H52H2-sds
PD1-C52H9 Canine Canine PD-1 / PDCD1 Protein, His Tag (MALS verified)
PD1-C52H9-structure
PD1-C52H9-sds
PD1-H82A4 Human Biotinylated Human PD-1 / PDCD1 Protein, Mouse IgG2a Fc,Avitag™ (MALS verified)
PD1-H82A4-structure
PD1-H82A4-sds
PD1-R52H3 Rhesus macaque Rhesus macaque PD-1 / PDCD1 Protein, His Tag (MALS verified)
PD1-R52H3-structure
PD1-R52H3-sds
PD1-H52H6 Human Human PD-1 / PDCD1 Full Length Protein, His Tag
PD1-H52H6-structure
PD1-H52H6-sds
PD1-H82F4 Human Biotinylated Human PD-1 / PDCD1 Protein, Fc,Avitag™,His Tag (MALS verified)
PD1-H82F4-structure
PD1-H82F4-sds
PD1-C82E6 Cynomolgus Biotinylated Cynomolgus PD-1 / PDCD1 Protein, His,Avitag™
PD1-C82E6-structure
PD1-C82E6-sds
PD1-HP2F2 Human PE-Labeled Human PD-1 / PDCD1 Protein, Fc,His Tag (recommended for neutralizing assay) (Site-specific conjugation)
PD1-HP2F2-structure
PD1-H5255 Human Human PD-1 / PDCD1 Protein, Mouse IgG2a Fc Tag (HPLC-verified)
PD1-H5255-structure
PD1-H5255-sds
PD1-H5255-hplc
PD1-H522a Human Human PD-1 / PDCD1 Protein, His Tag, low endotoxin (MALS verified)
PD1-H522a-structure
PD1-H522a-sds
EPM-V1 Mouse ELISA Assay Kit for Anti-PD-1 h-mAb in Mouse Serum
PD1-H5259 Human Human PD-1 / PDCD1 Protein, Llama IgG2b Fc Tag, low endotoxin (MALS verified)
PD1-H5259-structure
PD1-H5259-sds
EPH-V1 Human ELISA Assay Kit for Anti-PD-1 h-mAb in Human Serum
PD1-H82F1 Human Biotinylated Human PD-1 / PDCD1 Protein, Fc,Avitag™ (MALS verified)
PD1-H82F1-structure
PD1-H82F1-sds
PD1-RB5251 Rabbit Rabbit PD-1 / PDCD1 Protein, Fc Tag
PD1-RB5251-structure
PD1-RB5251-sds
PD1-R52H2 Rat Rat PD-1 / PDCD1 Protein, His Tag
PD1-R52H2-structure
PD1-R52H2-sds
PD1-H82E4 Human Biotinylated Human PD-1 / PDCD1 Protein, Avitag™,His Tag (recommended for biopanning) (MALS verified)
PD1-H82E4-structure
PD1-H82E4-sds
PD1-R52H0 Rabbit Rabbit PD-1 / PDCD1 Protein, His Tag (MALS verified)
PD1-R52H0-structure
PD1-R52H0-sds
PD1-M82F4 Mouse Biotinylated Mouse PD-1 / PDCD1 Protein, Fc,Avitag™ (MALS verified)
PD1-M82F4-structure
PD1-M82F4-sds
PD1-R5253 Rat Rat PD-1 / PDCD1 Protein, Fc Tag (MALS verified)
PD1-R5253-structure
PD1-R5253-sds
PD1-M5259 Mouse Mouse PD-1 / PDCD1 Protein, Fc Tag
PD1-M5259-structure
PD1-M5259-sds
PD1-C5254 Cynomolgus Cynomolgus PD-1 / PDCD1 Protein, Fc Tag (MALS verified)
PD1-C5254-structure
PD1-C5254-sds
PD1-H5257 Human Human PD-1 / PDCD1 Protein, Fc Tag, low endotoxin (MALS verified)
PD1-H5257-structure
PD1-H5257-sds
PD1-H5221 Human Human PD-1 / PDCD1 Protein, His Tag (MALS verified)
PD1-H5221-structure
PD1-H5221-sds
ACRO Quality

カスタマーレビュー

Synonym Name

PDCD1,PD1,CD279,SLEB2

Background

How a therapeutic antibody is metabolized in the body is pertinently relevant to its efficacy. Therefore, pharmacokinetics study is an important part of the drug development. PD-1 is probably the most targeted molecule in today’s pharmaceutical industry, thanking to the clinical success of Keytruda® and Opdivo®. Many investigational anti-PD-1 mAbs are being developed. There is a growing need for a standard assay that can be used to facilitate the study of their pharmacokinetics.

Clinical and Translational Updates

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