ログイン 会員登録
icon_bulk_order一括注文 Acrobiosystems for English
Promotion
Recombinantタンパク質s ClearClear history
Recombinantタンパク質s CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP IL-2 Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
phone
Your Position: ホーム > Nectin-1

Nectin-1

概要

Name:Pregnane X receptor
Target Synonym:SXR,Nuclear Receptor Subfamily 1, Group I, Member 2,Pregnane X Nuclear Receptor Variant 2,ONR1,PAR1,PAR2,PARq,BXR,PAR,PRR,SAR,Pregnane X Receptor,PXR,NR1I2,Nuclear Receptor Subfamily 1 Group I Member 2,Orphan Nuclear Receptor PXR,Steroid And Xenobiotic Receptor,Orphan Nuclear Receptor PAR1
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

製品リスト製品比較と製品注文

製品> フィルター結果
製品仕様別：
製品カテゴリー別：
種類別：
タグ別：
コンジュゲート：
製造番号 種類 製品説明 構造 純度 特徴
PV1-H5253 Human Human Nectin-1 / PVRL1 / CD111 Protein, Fc Tag
PV1-H5253-structure
PV1-H5253-sds
PV1-H5223 Human Human Nectin-1 / PVRL1 / CD111 Protein, His Tag
PV1-H5223-structure
PV1-H5223-sds
ACRO Quality

生物活性データの一部

PV1-H5253-BLI
Nectin-1 BLI

Loaded Human Nectin-1, Fc Tag (Cat. No. PV1-H5253) on Protein A Biosensor, can bind Human Nectin-4, His Tag (Cat. No. NE4-H52H3) with an affinity constant of 0.271 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
PV1-H5253-BLI
Nectin-1 BLI

Loaded Cynomolgus Nectin-4, His Tag (Cat. No. NE4-C52H4) on HIS1K Biosensor, can bind Human Nectin-1, Fc Tag (Cat. No. PV1-H5253) with an affinity constant of 0.23 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Synonym Name

PVRL1,Nectin-1,CD111,CLPED1,ED4,HIgR,HVEC,OFC7,PRR,PRR1,PVRR,PVRR1,SK-12

Background

Poliovirus receptor-related protein 1 (PVRL1) is also known as Herpes virus entry mediator C (HveC), Herpesvirus Ig-like receptor (HIgR), Nectin-1, CD antigen CD111, PVRL1 / Nectin-1 / CD111 belongs to the nectin family. PVRL1 / Nectin-1 is a membrane protein with three extracellular immunoglobulin domains, a single transmembrane helix and a cytoplasmic tail. The protein can mediate Ca2+-independent cellular adhesion further characterizing it as IgSF cell adhesion molecule (IgSF CAM). PVRL1 is adhesion molecule found in a wide range of tissues. PVRL1 / Nectin-1 promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4.

Clinical and Translational Updates

公開薬物情報

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Crotamiton/Diphenhydramine Hydrochloride/Vitamin E/Glycyrrhetinic Acid Approved 安夫康 Dermatitis Details
Crotamiton/Diphenhydramine Hydrochloride/Vitamin E/Glycyrrhetinic Acid Approved 安夫康 Dermatitis Details

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Vitamin E/Ascorbic Acid Phase 3 Clinical Advanced Medical Projects Fragile X Syndrome; Neuralgia Details
Lidocaine/Allantoin/Glycyrrhetinic Acid/Vitamin E Phase 2 Clinical Hemorrhoids; Warts; Pain; Fissure in Ano Details
Vitamin E/Ascorbic Acid Phase 3 Clinical Advanced Medical Projects Fragile X Syndrome; Neuralgia Details
Lidocaine/Allantoin/Glycyrrhetinic Acid/Vitamin E Phase 2 Clinical Hemorrhoids; Warts; Pain; Fissure in Ano Details

This web search service is supported by Google Inc.

totopphone
Call us
お問い合わせ
グローバル：+1 800-810-0816(Toll Free)
日本：+(0)81-50-547-99099
Email
メールアドレス
order.jp@acrobiosystems.com
Fax
ファックス
+1 888-377-6111
Address
株式会社アクロバイオシステムズ
〒157-0066
東京都世田谷区成城1丁目26番9-101号

アクロバイオシステムズの公式アカウント

linkedin twitter facebook youtube

お問い合わせ（半角英文字で入力してください）

Copyright © 2017 ACROBiosystems. All Rights Reserved
Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap