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Here come GMP Grade Cytokines!Free Sample is available! Here come GMP Grade Cytokines!Free Sample is available!
Flow Cytometry assay shows that Human CD27 Protein, Mouse IgG2a Fc Tag (Cat. No. CD7-H5257) can bind to Raji cells Surface Human CD70. The concentration of CD27 used is 10 μg/mL (Routinely tested).
Immobilized Human CD27, His Tag (Cat. No. CD7-H522b) at 2 μg/mL (100 μL/well) can bind Biotinylated Human CD27 Ligand Protein, Avitag,Fc Tag with a linear range of 1-31 ng/mL (QC tested).
The purity of Human CD27, His Tag (Cat. No. CD7-H522b) is more than 85% and the molecular weight of this protein is around 32-47 kDa verified by SEC-MALS.
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Boserolimab | MK-5890 | Phase 2 Clinical | Merck & Co Inc | Solid tumours; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Varlilumab | CDX-1127 | Phase 2 Clinical | Celldex Therapeutics | Gallbladder Neoplasms; Lymphoma, Primary Effusion; Cholangiocarcinoma; Lymphoma, Mantle-Cell; Bile Duct Neoplasms; Urologic Neoplasms; Astrocytoma; Lymphoma, T-Cell; Burkitt Lymphoma; Lymphoma, Non-Hodgkin; Plasmablastic Lymphoma; Lung Neoplasms; Urogenital Neoplasms; Lymphoma; Glioma; Melanoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Biliary Tract Neoplasms; Head and Neck Neoplasms; Kidney Neoplasms; Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Lymphomatoid Granulomatosis; Skin Neoplasms; Lymphoma, B-Cell; Kidney Diseases; Neoplasms; Glioblastoma; Triple Negative Breast Neoplasms; Urologic Diseases; Urinary Bladder Neoplasms; Oligodendroglioma; Prostatic Neoplasms | Details |
GEN-1053 | BNT-313; GEN-1053 | Phase 2 Clinical | Genmab A/S | Solid tumours | Details |
LOR-S03 | CDX-527 | Phase 1 Clinical | Celldex Therapeutics | Ovarian Neoplasms; Solid tumours; Liver Neoplasms; Head and Neck Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Neoplasms; Microsatellite instability-high cancer; Urinary Bladder Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Anti-CD27 monoclonal antibody (Aduro Biotech) | BION-1402 | Phase 1 Clinical | Aduro Biotech Inc | Neoplasms | Details |
Boserolimab | MK-5890 | Phase 2 Clinical | Merck & Co Inc | Solid tumours; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Varlilumab | CDX-1127 | Phase 2 Clinical | Celldex Therapeutics | Gallbladder Neoplasms; Lymphoma, Primary Effusion; Cholangiocarcinoma; Lymphoma, Mantle-Cell; Bile Duct Neoplasms; Urologic Neoplasms; Astrocytoma; Lymphoma, T-Cell; Burkitt Lymphoma; Lymphoma, Non-Hodgkin; Plasmablastic Lymphoma; Lung Neoplasms; Urogenital Neoplasms; Lymphoma; Glioma; Melanoma; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Biliary Tract Neoplasms; Head and Neck Neoplasms; Kidney Neoplasms; Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Lymphomatoid Granulomatosis; Skin Neoplasms; Lymphoma, B-Cell; Kidney Diseases; Neoplasms; Glioblastoma; Triple Negative Breast Neoplasms; Urologic Diseases; Urinary Bladder Neoplasms; Oligodendroglioma; Prostatic Neoplasms | Details |
GEN-1053 | BNT-313; GEN-1053 | Phase 2 Clinical | Genmab A/S | Solid tumours | Details |
LOR-S03 | CDX-527 | Phase 1 Clinical | Celldex Therapeutics | Ovarian Neoplasms; Solid tumours; Liver Neoplasms; Head and Neck Neoplasms; Stomach Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Neoplasms; Microsatellite instability-high cancer; Urinary Bladder Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung | Details |
Anti-CD27 monoclonal antibody (Aduro Biotech) | BION-1402 | Phase 1 Clinical | Aduro Biotech Inc | Neoplasms | Details |
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