Immobilized Fibronectin at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGA8 & ITGB1 Heterodimer Protein (Cat. No. IT1-H82Wb) with a linear range of 0.078-2.5 μg/mL (QC tested).
Immobilized Fibronectin fragment, premium grade (Cat. No. FIN-H5113) at 5 μg/mL (100 μL/well) can bind Human ITGA8&ITGB1 Heterodimer Protein, Twin-Strep Tag&Tag Free (Cat. No. IT1-H5283) with a linear range of 0.01-0.3 μg/mL (QC tested).
Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.