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Bevacizumab

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製造番号 種類 製品説明 構造 純度 特徴
BEB-Y10 Mouse Anti-Bevacizumab Antibody (AY10) (MALS verified, recommended for PK/PD)
BEB-Y10-sds
BEB-BY13 Mouse Biotinylated Anti-Bevacizumab Antibody (AY13) (recommended for PK/PD)
BEB-BY13-sds
BEB-Y9 Mouse Anti-Bevacizumab Antibody (AY9) (recommended for ADA assay)
BEB-Y9-sds
BEB-Y12 Mouse Anti-Bevacizumab Antibody (AY12) (recommended for neutralizing assay)
BEB-Y12-sds
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BEB-Y9-SPR
Bevacizumab SPR

Anti-Bevacizumab Antibody (AY9) (mouse IgG1, Cat. No. BEB-Y9) captured on CM5 chip via anti-mouse antibodies surface, can bind human bevacizumab with an affinity constant of 1.92 nM.

Protocol
BEB-Y12-SPR
Bevacizumab SPR

Anti-Bevacizumab Antibody (AY12) (mouse IgG1, Cat. No. BEB-Y12) captured on CM5 chip via anti-mouse antibodies surface, can bind human bevacizumab with an affinity constant of 0.08 nM.

Protocol

Synonym Name

Background

A recombinant humanized monoclonal IgG1 antibody that binds to and inhibits the biologic activity of human vascular endothelial growth factor (VEGF). Bevacizumab contains human framework regions and the complementarity-determining regions of a murine antibody that binds to VEGF. Bevacizumab is produced in a Chinese Hamster Ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin and has a molecular weight of approximately 149 kilodaltons.

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