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Your Position: ホーム > Protein > Complement Factor D > CFD-R5255

Rhesus macaque Complement Factor D / CFD Protein, Fc Tag

  • シノニム
    CFD,Adipsin,PFD,DF,Complement factor D
  • ソース
    Rhesus macaque Complement Factor D, Fc Tag (CFD-R5255) is expressed from human 293 cells (HEK293) and inactive. It contains AA Ile 26 - Ala 253 (Accession # H9EXC1-1).
    Predicted N-terminus: Ile 26
  • 分子特性
    Online(Ile 26 - Ala 253) H9EXC1-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 51.0 kDa. The protein migrates as 53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • エンドトキシン
    Less than 1.0 EU per μg by the LAL method.
  • 純度

    >95% as determined by SDS-PAGE.

  • 成分

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 再構成

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 保存

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. 4-8°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Rhesus macaque Complement Factor D, Fc Tag (Cat. No. CFD-R5255) SDS-PAGE gel

Rhesus macaque Complement Factor D, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • バックグラウンド
    Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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