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Your Position: ホーム > Protein > Integrin alpha 11 beta 1 > IT1-M52W5

Mouse Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free

  • シノニム
    Integrin alpha 11 beta 1,ITGA11&ITGB1
  • ソース
    Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 23 - Pro 1141 (ITGA11) & Gln 21 - Asp 728 (ITGB1) (Accession # P61622-1(ITGA11) & P09055-1(ITGB1)).
    Predicted N-terminus: Phe 23 (ITGA11) & Gln 21 (ITGB1)
  • 分子特性
    Online(Phe 23 - Pro 1141 (ITGA11) & Gln 21 - Asp 728 (ITGB1)) P61622-1 (ITGA11) & P09055-1 (ITGB1)

    Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA11 and ITGB1, has a calculated MW of 132.0 kDa (ITGA11) and 83.5 kDa (ITGB1). Subunit ITGA11 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 105-116 kDa and 150 kDa due to glycosylation.

  • エンドトキシン
    Less than 1.0 EU per μg by the LAL method.
  • 純度

    >90% as determined by SDS-PAGE.

  • 成分

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 再構成

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 保存

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-M52W5) SDS-PAGE gel

Mouse ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • バックグラウンド
    Integrin alpha 11 beta 1 is a receptor for collagen. The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids. The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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