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Your Position: ホーム > Protein > MOG > MOG-H52H3

Human MOG Protein, His Tag (MALS verified)

  • Synonym
    MOG,BTN6,BTNL11,MOGIG2,NRCLP7,Myelin oligodendrocyte glycoprotein
  • Source
    Human MOG, His Tag(MOG-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 30 - Gly 154 (Accession # Q16653-1).
    Predicted N-terminus: Gly 30
  • Molecular Characterization
    MOG Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 16.2 kDa. The protein migrates as 20-24 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
MOG SDS-PAGE

Human MOG, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
MOG MALS images

The purity of Human MOG, His Tag (Cat. No. MOG-H52H3) is more than 85% and the molecular weight of this protein is around 16-24 kDa verified by SEC-MALS.

  • Background
    Myelin oligodendrocyte glycoprotein (MOG), is a single-pass transmembrane glycoprotein of the immunoglobulin (Ig) superfamily. MOG is a myelin protein exclusively expressed in the CNS at the outermost surface of myelin sheaths and oligodendrocyte membranes. This makes MOG a potential target of cellular and humoral immune responses in inflammatory demyelinating diseases. Due to its late postnatal developmental expression, MOG is an important marker for oligodendrocyte maturation.
  • Clinical and Translational Updates

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