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Your Position: ホーム > Protein > CDCP1 > CD1-M52H3

Mouse CDCP1 Protein, His Tag (MALS verified)

  • Synonym
    CUB domain-containing protein 1,CDCP1,CD318,Membrane glycoprotein gp140,Subtractive immunization M plus HEp3-associated 135 kDa protein,SIMA135,Transmembrane and associated with src kinases,TRASK,UNQ2486,PRO5773
  • Source
    Mouse CDCP1 Protein, His Tag(CD1-M52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 30 - Leu 666 (Accession # Q5U462).
    Predicted N-terminus: Ser 30
  • Molecular Characterization
    CDCP1 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 73.7 kDa. The protein migrates as 90-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CDCP1 SDS-PAGE

Mouse CDCP1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
CDCP1 MALS images

The purity of Mouse CDCP1 Protein, His Tag (Cat. No. CD1-M52H3) is more than 85% and the molecular weight of this protein is around 85-115 kDa verified by SEC-MALS.

  • Background
    CUB domain-containing protein 1, also know as CDCP1. CDCP1 is a cell surface glycoprotein that has been recognized both as a tumour marker and as a potential target to disrupt progression of cancer. CDCP1 has been shown to modulate cellsubstratum adhesion and motility in colon cancer cell lines.
  • Clinical and Translational Updates

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