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Your Position: ホーム > Protein > IgG1 Fc > IG1-HC2H3

Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag-Cy5

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    IgG1
  • Source
    Human IgG1 Fc Protein, His Tag-Cy5(IG1-HC2H3) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (C103S, M135Y, S137T, T139E, H316K, N317F) (Accession # P01857-1 (C103S, M135Y, S137T, T139E, H316K, N317F)).
    Predicted N-terminus: Glu 99
  • Molecular Characterization
    IgG1 Fc Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 28 kDa.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
  • Clinical and Translational Updates

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価格(JPY) : 89,320

価格(JPY) : 554,400

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