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Your Position: ホーム > Protein > MRC2 > MR2-H52H3

Human MRC2 Protein, His Tag (MALS verified)

  • Synonym
    CD280, CLEC13E, ENDO180, UPARAP
  • Source
    Human MRC2 Protein, His Tag(MR2-H52H3)  is expressed from human 293 cells (HEK293). It contains AA Gly 31 - Ala 1414 (Accession # Q9UBG0).
    Predicted N-terminus: Gly 31
  • Molecular Characterization
    MRC2 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 158.0 kDa. The protein migrates as 170-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker  under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

SDS-PAGE
MRC2 SDS-PAGE

Human MRC2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
MRC2 MALS images

The purity of Human MRC2 Protein, His Tag (Cat. No. MR2-H52H3) is more than 90% and the molecular weight of this protein is around 175-215 kDa verified by SEC-MALS.

  • Background
    This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II
    domain and multiple C-type lectin-like domains.  The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands.  Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
  • Clinical and Translational Updates

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