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Your Position: ホーム > Cell Grade Beads > VCAM-1 > MBS-C019

ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells)

ProductSizeAmount
ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells)2.5 mg2.5 × 10⁷ beads
10 mg (2.5 mg × 4)1.0 × 10⁸ beads
  • Background
    ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5) , and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.
  • Source
    ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface and coupled with biotinylated Human VCAM-1 / CD106 Protein, expressed from human 293 cells (HEK293) and contains AA Phe 25 - Glu 698(Accession # P19320-1).
  • Application
    ActiveMax® Human VCAM-1 / CD106 μBeads, premium grade (for cells) is designed to synergistically activate Notch signaling in hematopoietic stem/progenitor cells (HSPCs). The synergistic interactions between Notch ligand Delta-like 4 and VCAM-1 are leveraged to enhance Notch signaling to support efficient T-cell lineage commitment, so the beads is recommended to use for in vitro production of induced pluripotent stem cell derived T cells coordinating with ActiveMax® Human DLL4 μBeads, premium grade (Cat. No. MBS-C013).
    *We also carry ActiveMax® Streptavidin μBeads, premium grade (for cells)(Cat. No. MBS-C009),and it can be used for convenient preparation of your own sterile protein/antibody coupled beads for cell based assay, cell sorting and other applications. The ActiveMax® Streptavidin μBeads, premium grade can also be used together with other ActiveMax® μBeads, premium grade as Isotype control.
  • Reconstitution

    See Certificate of Analysis (CoA) for detailed instruction.

  • Storage
    This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.Please avoid repeated freeze-thaw cycles after reconstitution. Immediate use after reconstitution is highly recommended.
  • Sterility
    Negative
  • Endotoxin
    Less than 0.002 EU per μg by the LAL method.
  • Important Note
    This product is for research use only and not intended for therapeutic or in vivo diagnostic use.
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

Typical Data Please refer to DS document for the assay protocol.
 VCAM-1 TYPICAL DATA

Assay of human VCAM-1 / CD106 protein on the μBeads surface by Flow cytometry. The human VCAM-1 / CD106 protein conjugated on the μBeads (Cat. No. MBS-C019) surface were fluorescently stained using PE anti-human CD106 Antibody, analyzed by flow cytometry (QC tested).

Application Data
 VCAM-1 APPLICATION DATA

Combinations of ActiveMax® Human DLL4 μBeads (Cat. No. MBS-C013) and ActiveMax® Human VCAM-1 / CD106 μBeads (Cat. No. MBS-C019) could efficiently induce hematopoietic stem cells differentiation into CD56+ NK cells after 20 days of culture, with expression of CD56, NKp46, NKG2D, NKp30 and NKp44.

  • Clinical and Translational Updates

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ETD of in-stock products: 4 business days

価格(JPY) : 500,640

価格(JPY) : 1,228,920

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  • Number of Drugs in Clinical Trials:1 Details
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